Coffee and Your Brain
Name Date
Predict
Many adults drink coffee in the morning to wake up. Coffee has a chemical in it called caffeine. Does the caffeine in coffee give your body energy?
Circle one. Yes / No
Why?
Watch
- Coffee doesn’t give you energyyoutube.com/shorts/qIIaPqW8qkk
Word of the day
Adenosine (uh-DEN-uh-seen). A molecule found in all living cells. In the brain, adenosine builds up while you’re awake and helps signal that you’re tired.
| Word part | Comes from | Meaning |
|---|---|---|
| aden- | Greek adḗn | gland |
| -os- | ribose | a kind of sugar |
| -ine | French and Latin | an ending for chemical names |
- Your adenoids, at the top of your throat, have the same aden- root.
- Caffeine has the same -ine ending. Its name comes from café, the French word for coffee.
Bonus word. Receptor (rih-SEP-tur). A protein on a cell with a spot, like a seat, that one kind of molecule fits into. The word comes from Latin and is related to the word receive.
Questions
Your brain uses energy all day long. Adenosine is a leftover from the brain’s energy use, and it builds up while you are awake. As adenosine builds up, what message does it send your brain?
Hint. Think about how you feel at the end of a long day.
Adenosine sends its message by fitting into receptors on brain cells. In the video, Raven says caffeine is shaped enough like adenosine to sit in the same receptors. What happens to the tired message when caffeine takes adenosine’s seat?
Circle one. The tired message gets stronger / The tired message gets blocked / The adenosine turns into energy
Hint. Caffeine fits in the receptor, but caffeine doesn’t send the tired message.
In the video, Raven says adenosine keeps building up while caffeine sits in the receptors. What happens when the caffeine finally leaves adenosine’s receptors?
Hint. Think about all the adenosine that was waiting for a receptor.
When you drink coffee, caffeine moves from your small intestine into your blood. Your blood carries caffeine to your brain and your heart. Name two body systems that caffeine travels through or changes.
Hint. Follow the caffeine from your mouth to your brain. Which body systems move the caffeine along the way?
Exit ticket
In the video, Raven says coffee is not giving you energy. What does the caffeine in coffee do in your brain instead?
Hint. Think about adenosine and its receptors. What does caffeine do when it sits in a receptor?
Sources
- Christopher Drake, Timothy Roehrs, John Shambroom and Thomas Roth, Henry Ford Hospital Sleep Disorders & Research Center in Detroit, Journal of Clinical Sleep Medicine, 2013
- Review by Carolin Reichert (University Psychiatric Clinics Basel), Tom Deboer (Leiden University Medical Center) and Hans-Peter Landolt (University of Zürich), Journal of Sleep Research, 2022
- Review by Jennifer Temple (University at Buffalo) with colleagues at Aix Marseille University and Wayne State University, Frontiers in Psychiatry, 2017
- D. Robertson, J. A. Oates and colleagues, New England Journal of Medicine, 1978
- J. P. DiMarco and the Adenosine for PSVT Study Group, led from the University of Virginia, Annals of Internal Medicine, 1990
- J. A. Nathanson, Science, 1984
- ChEBI records in PubChem, Caffeine and adenosine
- Vision and Change core concepts and competencies, as summarized in Brownell and others, CBE Life Sciences Education, 2014
- Emergency use of adenosine, Gebril and Hawes, Emergency Medicine Journal, 2012
- Word origins from Dictionary.com: adenosine, adenine, adeno-, ribose, arabinose, gum arabic, -ine, caffeine, coffee, adenoid, receptor, antagonist, antagonize
- Spanish and French spellings from Wiktionary
- Instagram original of the video, not linked because Instagram needs a login
- Transcript from the posted video on YouTube