The Lizard Behind Ozempic
- Time
- 23 minutes
- Materials needed
- A calculator or scratch paper
- Time
- 38 minutes
- Materials needed
- A calculator or scratch paper
- Time
- 35 minutes
- Materials needed
- A calculator or scratch paper
Sources
- John Eng, an endocrinologist at the Bronx VA Medical Center, with W. A. Kleinman, L. Singh, G. Singh and Jean-Pierre Raufman, Journal of Biological Chemistry, 1992
- R. Göke, H. C. Fehmann, T. Linn, H. Schmidt, M. Krause, John Eng and B. Göke, Journal of Biological Chemistry, 1993
- Y. E. Chen and D. J. Drucker, Journal of Biological Chemistry, 1997
- C. M. Christel and D. F. DeNardo, Comparative Biochemistry and Physiology A, 2006
- R. Mentlein, B. Gallwitz and W. E. Schmidt, European Journal of Biochemistry, 1993
- C. F. Deacon, L. B. Knudsen, K. Madsen, F. C. Wiberg, O. Jacobsen and J. J. Holst, University of Copenhagen and Novo Nordisk, Diabetologia, 1998
- Reviews by Drucker, Habener and Holst, and by T. D. Müller and colleagues, Journal of Clinical Investigation, 2017 and Molecular Metabolism, 2019
- US Food and Drug Administration prescribing labels, Byetta label and Ozempic label
- Golden Goose Award, John Eng awardee page and 2013 announcement, for Eng’s work at the Bronx VA, the 1992 discovery and the path to Byetta
- Jake Currie, “How the Gila Monster Gave the World Ozempic,” Nautilus, 2026, for Eng’s title as an endocrinologist
- Smithsonian’s National Zoo, Gila monster
- UniProt P01275, the human proglucagon sequence, for GLP-1’s first five amino acids
- Vision and Change core concepts and competencies, as summarized in Brownell and others, CBE Life Sciences Education, 2014
- Word origins from Dictionary.com: insulin, -in, insula, insular, homeostasis, homeo-, stasis, peninsula, hemostasis, hemo-, thermostat, insulate, homeomorphism, Gila monster
- Spanish, French and Italian spellings from Wiktionary: insula, insulin